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Cayman Chemical NaloxonazInhydrochlorIde 10mg

Supplier: Cayman Chemical 2195010 MG
A μ-opioid receptor antagonist (Ki = 0.054 nM in a radioligand binding assay); selective for μ-opioid over κ- and δ-opioid receptors (Kis = 11 and 8.6 nM, respectively, in radioligand binding assays); selectively binds to high-affinity µ1-opioid over μ- and δ-opioid receptors (Kds = 0.1, 2, and 5 nM, respectively); reverses sufentanil-induced antinociception, hypercapnia, and hypoxia in rats at 0.16 mg/kg; reduces ethanol self-administration and food intake in rats at 10 mg/kg; inhibits cocaine-induced place preference in rats at 20 mg/kg
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