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Medchemexpress LLC Namitecan (ST-1968) | 372105-27-6 | 98.0% | 434.44 | 50 MG
Supplier: Medchemexpress LLC HY1482150MG
Namitecan is a potent topoisomerase I inhibitor with antitumor properties. It is intended for research use only and not for sale to patients.
- Exhibits antitumor activity.
- Acts as a potent topoisomerase I inhibitor.
- Inhibits EGFR expression in various cell lines.
- Induces apoptosis in A431 and A431/TPT cells.
- Shows cytotoxicity against NCI-H460 and H460 NSCLC cells.
- Demonstrates synergistic antitumor effects in SCC models when combined with cetuximab.
- Achieves complete response rate in mice with A431 tumors.
- Soluble in DMSO (250 mg/mL).
- Can be stored as powder at -20°C for 3 years or 4°C for 2 years.
- Can be stored in solvent at -80°C for 2 years or -20°C for 1 year.
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