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Medchemexpress LLC Nampt-IN-10 (TFA) | 2567724-20-1 | >98.6% | 701.59 | 25 MG
Supplier: Medchemexpress LLC 25MGHY147193
Nampt-IN-10 TFA (compound 4) is a Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitor. It shows cellular potency to A2780 and CORL23 cell lines with IC50s of 5 and 19 nM, respectively. Nampt-IN-10 TFA can be used as a novel non-antimitotic payload for ADCs.
- Shows cellular potency to A2780, CORL23, and c-Kit and HER2 expressing cell lines.
- IC50 values are 5 nM (A2780), 19 nM (CORL23), 2 nM (NCI-H526 with c-Kit expressing), 0.4 nM (MDA-MB453 with HER2 expressing), and 1 nM (NCI-N87 with HER2 expressing).
- Can be used as a novel non-antimitotic payload for ADCs.
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