Medchemexpress LLC Nampt-IN-3 | 2121591-52-2 | 99.0% | 503.55 | 100 MG

Supplier:  Medchemexpress LLC HY10870150MG

Nampt-IN-3 (Compound 35) simultaneously inhibits nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. It effectively induces cell apoptosis and autophagy, leading to cell death.

• Inhibits nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM.
• Effectively induces cell apoptosis and autophagy.
• Leads to cell death.
• Demonstrates cytotoxicity in human HCT116 cells with an IC50 of 2.4 μM.
• Demonstrates cytotoxicity in human HepG2 cells with an IC50 of 4.5 μM.
• Demonstrates cytotoxicity in human MDA-MB-231 cells with an IC50 of 10 μM.

Catalog No. 50-003-44866