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Medchemexpress LLC Nampt-IN-5 | 2380013-17-0 | >98.0% | 50 MG
SDP

Catalog No. 5000340195
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Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor that also inhibits CYP3A4 activity. It exhibits cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23 cell lines, respectively, demonstrating antiproliferative effects. In vivo, it causes significant body weight loss in nude mice and shows favorable ADME data.

  • Potent NAMPT inhibitor
  • Inhibits CYP3A4 activity
  • Exhibits antiproliferative activity against A2780 and COR-L23 cell lines
  • Shows good ADME data in vitro
  • Induces significant body weight loss in nude mice in vivo

Catalog No. 50-003-40195 Supplier Medchemexpress LLC Supplier No. HY13060650MG
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Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor that also inhibits CYP3A4 activity. It exhibits cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23 cell lines, respectively, demonstrating antiproliferative effects. In vivo, it causes significant body weight loss in nude mice and shows favorable ADME data.

  • Potent NAMPT inhibitor
  • Inhibits CYP3A4 activity
  • Exhibits antiproliferative activity against A2780 and COR-L23 cell lines
  • Shows good ADME data in vitro
  • Induces significant body weight loss in nude mice in vivo

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