AdipoGen Nampt Visfatin h pAb CT

Supplier:  AdipoGen AG25A0027C100

Polyclonal Antibody. Recognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of ~54kDa by Western blot. Source Rabbit. Applications ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Nicotinamide phosphoribosyltransferase Nampt pre-B cell colony-enhancing factor PBEF Visfatin is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide NAD. Two forms of Nampt exist, an intracellular form iNampt and an extracellular form eNampt. While the function of iNampt as an essential and rate-limiting NAD biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity.

Catalog No. 50-256-3285