AdipoGen Nampt Visfatin ratrec

Supplier:  AdipoGen AG40A0058C050

Protein. Rat Nampt visfatin/PBEF aa 1-491 is fused at the N-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Purity >90% SDS-PAGE. Nicotinamide phosphoribosyltransferase Nampt pre-B cell colony-enhancing factor PBEF Visfatin is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide NAD. Two forms of Nampt exist, an intracellular form iNampt and an extracellular form eNampt. While the function of iNampt as an essential and rate-limiting NAD biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity.

Catalog No. 50-256-3030