Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Napabucasin 83280-65-3 5mg
Supplier: Apexbio Technology LLC B60295
Napabucasin (CAS 83280-65-3) also known as BBI608 is an orally bioavailable small molecule that targets STAT3 (signal transducer and activator of transcription 3) a regulator of cancer cell pluripotency and survival Napabucasin inhibits STAT3 transcriptional activity with IC50 values of 0 395 M in bulk cancer cells and 0 142 M in cancer stem cells In vitro it reduces cell viability migration colony formation and stemness marker expression induces cell cycle arrest and apoptosis and sensitizes cells to chemotherapy In vivo napabucasin suppresses tumor growth and recurrence and limits self-renewal and metastasis of cancer stem cells in xenograft models This compound is widely utilized in studies of cancer stemness and STAT3-driven oncogenesis
This item is not returnable.
View return policy
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?