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AdipoGen NAPRTase human rec His
Supplier: AdipoGen AG40T0105C050
Protein. Human NAPRTase is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 50mM HEPES/KOH pH 7.5 containing 300mM potassium chloride and 10mM DTT. Purity >98% SDS-PAGE. Human nicotinate phosphoribosyltransferase NAPRTase is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid NA to NA mononucleotide NaMN and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD biosynthesis pathway. Catalytic activity Beta-nicotinate D-ribonucleotide diphosphate = nicotinate 5-phospho-alpha-D-ribose 1-diphosphate.
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