Medchemexpress LLC Naquotinib mesylate | 1448237-05-5 | MFCD30496702 | 98.2% | 658.81 | C31H46N8O6S | 10 MG

Supplier:  Medchemexpress LLC HY1980310MG

Naquotinib mesylate is the mesylate salt of naquotinib, an orally available, irreversible, mutant-selective epidermal growth factor receptor (EGFR) inhibitor used in preclinical research. It preferentially inhibits common activating and resistance EGFR mutants while showing reduced potency against wild-type EGFR, making it useful for studies of mutant-selective signaling and resistance mechanisms.

• Mutant-selective irreversible EGFR inhibitor
• Potent against L858R, exon 19 deletion, and T790M mutants (IC50 8-33 nM)
• Lower potency toward wild-type EGFR (IC50 ~230 nM)
• Provided as a mesylate salt suitable for research applications
• Molecular formula C31H46N8O6S; molecular weight 658.81
• Reported research-grade purity approximately 98%

Catalog No. 50-002-97489