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Medchemexpress LLC Naratriptan (hydrochloride) | 143388-64-1 | 99.7% | 1 ML
Supplier: Medchemexpress LLC HYB0197A10MM/1ML
Naratriptan hydrochloride is a selective 5-HT1B/1D receptor agonist known for its peripheral activity and good oral bioavailability. It induces cranial artery vasoconstriction and inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation, reducing sterile inflammation. This compound is primarily used in acute migraine research, focusing on cranial vascular and neuroinflammatory mechanisms.
- Selective 5-HT1B/1D receptor agonist
- Peripherally active with good oral bioavailability
- Induces cranial artery vasoconstriction
- Inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation
- Reduces sterile inflammation
- Targets human recombinant 5-HT1B and 5-HT1D receptors
- Used in research for acute migraine
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