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Medchemexpress LLC Naringenin chalcone | 73692-50-9 | MFCD00016762 | 100 MG
Supplier: Medchemexpress LLC HYN3007100MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It induces apoptosis and inhibits the production of MCP-1 and NO. This compound exhibits anticancer activity against glioblastoma and possesses anti-inflammatory and anti-allergic properties. Intended for research use only.
- Induces apoptosis in glioblastoma cells.
- Inhibits production of MCP-1, TNF-α, and NO in macrophages.
- Increases adiponectin mRNA levels and protein secretion in adipocytes.
- Reduces eosinophilic airway inflammation and airway hyperresponsiveness.
- Suppresses Th2 cytokine production and reduces mucus overproduction.
- Reduces tumor volume and weight in glioblastoma xenograft models.
- Increases plasma adiponectin levels in diabetic mice.
- Inhibits anaphylactic response to IgE-mediated passive cutaneous anaphylaxis.
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