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Cayman Chemical Nav1 7 Blocker 52 10mg
SDP

Supplier:  Cayman Chemical 3447710 MG

Encompass_Preferred

An inhibitor of Nav1.7 (IC50 = 0.17 µM); selective for Nav1.7 over hERG/Kv11.1, Nav1.5, and Nav1.8 (IC50s = >10, 1.1, and 2.2 µM, respectively) but does inhibit Nav1.3 and Nav1.4 (IC50s = 0.3 and 0.4 µM, respectively); inhibits formalin-induced flinching in a rat model of persistent pain at 20 and 30 mg/kg; increases latency to paw withdrawal in a hot plate test in a mouse model of CFA-induced inflammatory pain

Catalog No. 50-294-9064


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