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Cayman Chemical NavenIFle TIsue MR Ato647N 100

Supplier: Cayman Chemical 39219100 RXN

A σ1 receptor agonist inhibits reductions in mitochondrial oxygen consumption and lipid peroxidation induced by AB (25-35) in isolated mouse hippocampus at 1 mg/kg improves deficits in novel object recognition induced by AB (25-35) in mice as well as reduces tau phosphorylation and AB (1-42) levels in the hippocampus in the same model at 1 mg/kg increases the latency to fall in the rotarod test reduces gait impairments and reduces increases in the mean acoustic startle response in an Mecp2-/- mouse model of Rett syndrome at 30 mg/kg per day
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