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Medchemexpress LLC Navlimetostat hydrochloride | 00-00-0 | 99.2% | C23H19Cl2FN6O2 | 10MG
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Supplier:  Medchemexpress LLC HY139611C10MG

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Navlimetostat hydrochloride is a research-grade small-molecule inhibitor selective for the PRMT5-MTA complex. It demonstrates potent biochemical and cellular activity and is used in preclinical studies to probe PRMT5 biology and evaluate antineoplastic effects, with reported selectivity in MTAP-deleted models.

  • Potent inhibitor of the PRMT5-MTA complex (IC50 3.6 nM).
  • Inhibits PRMT5 enzymatic activity (IC50 20.5 nM).
  • Shows cellular selectivity in MTAP-deleted models (cell viability 12 nM vs 890 nM in parental cells).
  • High purity (99.2%).
  • Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
  • Suitable for preclinical research; store sealed away from moisture.

Catalog No. 50-002-59650


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