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Medchemexpress LLC Navtemadlin | 1352066-68-2 | 99.6% | 25 MG
SDP

Supplier:  Medchemexpress LLC HY1229625MG

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Navtemadlin is a potent, selective, orally active small-molecule inhibitor of the p53-MDM2 interaction. It stabilizes and activates p53, producing antiproliferative effects in p53 wild-type cells, and is used in cell-based and target-validation oncology research.

  • Potent inhibition of p53-MDM2 interaction (IC50 0.6 nM).
  • High binding affinity for MDM2 (Kd 0.045 nM).
  • Orally active small molecule suitable for cell-based assays.
  • Useful for p53 pathway activation and oncology target validation studies.
  • Chemical formula C28H35Cl2NO5S; molecular weight 568.6 g/mol.

Catalog No. 50-002-30681


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