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Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13998950MG

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NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist. It binds to HIV-1 gp120 and demonstrates significant antiviral activity. This compound exhibits low cytotoxicity with a CC50 >100 μM, making it suitable for various research applications.

  • Potent HIV-1 entry antagonist with IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses
  • Binds to HIV-1 gp120
  • Exhibits potent antiviral activity
  • Low cytotoxicity (CC50 > 100 μM)
  • Anti-HIV-1 activity (IC50=0.16 μM) in single-cycle (TZM-bl cells) assay
  • No induced toxicity in U87-CD4-CXCR4 cell line at assay doses

Catalog No. 50-003-49735


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