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Medchemexpress LLC Nbd-557 | 333352-59-3 | 99.4% | C17H24BrN3O2 | 100 MG
Supplier: Medchemexpress LLC HY76649100MG
NBD-557 is a small molecule organic compound identified as a potent HIV-1 inhibitor. It targets viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4, without affecting later stages of the HIV-1 life cycle such as reverse transcriptase, integrase, or protease.
- Potent cell and virus-cell fusion inhibitory activity
- Active against both X4 and R5 viruses in CXCR4 and CCR5 expressing cell lines
- Binds to unliganded HIV-1 gp120
- Active against laboratory-adapted strains and primary isolates of HIV-1
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