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Medchemexpress LLC NBD-557 | 333352-59-3 | 99.4% | C17H24BrN3O2 | 25 MG
Supplier: Medchemexpress LLC 25MGHY76649
NBD-557 is a small molecule organic compound identified as a potential HIV-1 inhibitor. It targets viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the CD4 receptor without affecting later stages of the HIV-1 life cycle.
- Exhibits potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Active against X4 and R5 viruses, and laboratory-adapted HIV-1 strains, including an AZT-resistant strain.
- Binds to unliganded HIV-1 gp120, but not to the cellular receptor CD4.
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