NBD-Pen is the first fluorescence probe for lipid radicals, offering high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). It specifically detects lipid-derived radicals over other reactive species found in biological systems, including H2O2, ClO-, O2•-, and •OH. NBD-Pen directly detects lipid radicals in living cells through turn-on fluorescence. It has been observed to decrease inflammation, apoptosis, and oxidative stress markers, and can be utilized in various disease models such as hepatic carcinoma.
- First fluorescence probe for lipid radicals.
- High selectivity and sensitivity (λex: 470 nm, λem: 530 nm).
- Specifically detects lipid-derived radicals over other reactive species (H2O2, ClO-, O2•-, and •OH).
- Directly detects lipid radicals in living cells by turn-on fluorescence.
- Decreases inflammation, apoptosis, and oxidative stress markers.
- Applicable for studying various disease models, including hepatic carcinoma.