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Medchemexpress LLC NBI-31772 | 374620-70-9 | 98.9% | 341.27 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11013510MG

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NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). It has neuroprotective effects, reducing infarct volume during cerebral ischemia. It can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes and increases the effect of IGF3 on zebrafish oocyte maturation.

  • Reduces infarct volume during cerebral ischemia
  • Restores or enhances proteoglycan synthesis in osteoarticular chondrocytes
  • Increases the effect of IGF3 on zebrafish oocyte maturation
  • Stimulates IGF-1-dependent proteoglycans in human OA chondrocytes
  • Stimulates rabbit articular chondrocyte-associated proteoglycans
  • Induces maturation of zebrafish oocytes
  • Reduces total and cortical infarct volume in MCAO model rats
  • Reduces cortical infarct size and brain swelling in intraluminal suture MCAO model rats

Catalog No. 50-003-44319


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