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Medchemexpress LLC NBQX disodium | 479347-86-9 | C12H6N4Na2O6S | 5 MG
Supplier: Medchemexpress LLC HY15068A5MG
NBQX disodium is a highly selective and competitive AMPA receptor antagonist. It exhibits neuroprotective and anticonvulsant activity by targeting AMPA and kainate binding sites, with minimal affinity for the glutamate recognition site on the NMDA receptor complex. It has demonstrated efficacy in decreasing PTZ-induced seizures and neuroprotection in focal ischemia models.
- Highly selective and competitive AMPA receptor antagonist
- Exhibits neuroprotective activity
- Shows anticonvulsant activity
- High affinity for AMPA and kainate binding sites
- Minimal affinity for the glutamate recognition site on the NMDA receptor complex
- Decreases seizures induced by PTZ
- Neuroprotective in focal ischemia models
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