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Cayman Chemical ncalctol 10mg
Supplier: Cayman Chemical 3728810 MG
A vitamin D receptor agonist; induces reporter gene expression in VDR-expressing COS-1 cells at 1 nM; induces differentiation of HL-60 and MG-63 cells (EC50s = 6.2 and 0.18 nM, respectively); reduces the proliferation of MCF-7 cells (EC50 = 4.1 nM); protects primary human keratinocytes against DNA damage induced by UVB irradiation; inhibits acetylcholine- or ATP-induced contractions of aortic rings isolated from spontaneously hypertensive rats at 100 nM; unlike calcitriol, it does not increase serum calcium levels or decrease tibia calcium levels in mice at 80 UG/kg
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