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Eurofins Discoverx PathHunter NCI-H460 CDC25A Degradation Cell Line, 2 vials. (93-0776C12)

Supplier:  Eurofins Discoverx 930776C12

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The PathHunter NCI-H460 CDC25A Degradation Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the cell cycle checkpoint pathway. This cell line enables detection of levels of CDC25a, allowing for assessment of CHK-1-activation-induced CDC25a degradation. This product uses EFC technology. The cell line included overexpresses CDC25a target protein fused to ProLabel. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of CDC25a EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.

Catalog No. 50-200-1292


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