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Medchemexpress LLC NCT-502 10mg | 1542213-00-2 | 395.45 g·mol⁻1 | C18H20F3N5S | 10 MG
Supplier: Medchemexpress LLC HY11724010MG
NCT-502 is a small-molecule inhibitor of human phosphoglycerate dehydrogenase (PHGDH). It reduces glucose-derived serine production and is cytotoxic to PHGDH-dependent cancer cells, making it suitable for biochemical and cellular studies of serine biosynthesis and metabolic vulnerabilities in cancer research.
- PHGDH inhibitor (IC50 3.7 μM).
- High purity (~98.59%).
- Molecular weight 395.45 g·mol⁻1; formula C18H20F3N5S.
- Soluble in DMSO (~130 mg/mL); sonication recommended for dissolution.
- Stable when stored as powder at -20°C (up to 3 years) or 4°C (up to 2 years).
- Recommended frozen storage for solutions: -80°C (up to 2 years) or -20°C (up to 1 year).
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