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Medchemexpress LLC NCT-506 | 2231098-99-8 | 99.95% | 478.54 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11227810MM/1ML

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NCT-506 is an orally bioavailable aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with an IC50 of 7 nM. It is intended for research use only.

  • Inhibits ALDH1A1, hALDH1A3, and hALDH2 with IC50s of 0.007±0.001, 16.4±3.99, and 21.5 μM, respectively.
  • Decreases cell viability with an EC50 of 45.6 μM in OV-90 cells (3D culture) after 6 days.
  • Inhibits MIA PaCa-2, OV-90, and HT-29 cells in aldefluor cell-based assays.
  • Shows enhanced inhibitory effects when combined with Paclitaxel in SKOV-3-TR cells.

Catalog No. 50-004-36618


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