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Medchemexpress LLC HY-127111 5mg Medchemexpress, NDI-091143 CAS:2375840-87-0 Purity:>98%
Supplier: Medchemexpress LLC HY1271115MG
Medchemexpress, HY-127111 5mg NDI-091143 CAS:2375840-87-0 NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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