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New England Biolabs, Inc. NEBNext Enzymatic Methyl-seq Conversion Module – 24 reactions
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Catalog No. NC1677458
Encompass

NEBNext Enzymatic Methyl-seq (EM-seq) is a new method for identification of 5-mC and 5-hmC. While bisulfite sequencing has been the gold standard for methylome analysis, this conversion treatment damages DNA, resulting in fragmentation, loss and bias. The NEBNext Enzymatic Methyl-seq Conversion Module provides an enzyme-based alternative to bisulfite conversion. For use in Illumina sequencing workflows, we recommend use of the NEBNext Enzymatic Methyl-seq Kit instead of this module. The full kit includes the EM-seq Adaptor, which has been optimized for high performance in the EM-seq workflow, as well as the high-efficiency Ultra II library prep reagents, and these components are not included in the Conversion Module.

Catalog No. NC1677458 Supplier New England Biolabs, Inc. Supplier No. E7125S
May include imposed supplier surcharges.
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NEBNext Enzymatic Methyl-seq (EM-seq) is a new method for identification of 5-mC and 5-hmC. While bisulfite sequencing has been the gold standard for methylome analysis, this conversion treatment damages DNA, resulting in fragmentation, loss and bias. The NEBNext Enzymatic Methyl-seq Conversion Module provides an enzyme-based alternative to bisulfite conversion. For use in Illumina sequencing workflows, we recommend use of the NEBNext Enzymatic Methyl-seq Kit instead of this module. The full kit includes the EM-seq Adaptor, which has been optimized for high performance in the EM-seq workflow, as well as the high-efficiency Ultra II library prep reagents, and these components are not included in the Conversion Module.

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