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Apexbio Technology LLC Necrostatin-1, 4311-88-0, MFCD00056916, 10 mg
Supplier: Apexbio Technology LLC A421310
MF: C13H13N3OS, MW: 259.33, Solubility: 12.97 mg/mL in DMSO, 13.29 mg/mL in EtOH with ultrasonic,insoluble in H2O. Necroptosis is a cellular mechanism of necrotic cell death induced by apoptotic stimuli in the form of death domain receptor engagement by their respective ligands under conditions where apoptotic execution is prevented. Necrostatin-1, identified as a small-molecule inhibitor of necroptosis, is also a selective allosteric inhibitor of the death domain receptorassociated adaptor kinase RIP1.
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