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AdipoGen Necrostatin-1 (25 mg)

Supplier: AdipoGen AGCR12900M025
Chemical. CAS: 4311-88-0. Formula: C13H13N3OS. MW: 259.3. Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase 1 (RIPK1) inhibitor. Used in inflammatory and degenerative disease models to target RIPK1. Suppresses autophagy and apoptosis in murine brain injury models. Cardioprotective and neuroprotective.
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