Ubpbio NECROSTATIN-1, 5MG
Manufacturer: Ubpbio F7100
Inhibitors – Necrostatin-1 (UBPBio catalog# F7100, F7101) – Necrostatin-1 is a potent inhibitor of necroptosis, a programmed and caspase-independent cell death mechanism. The death domain receptor-associated serine/threonine kinase RIP1 is essential for TNFα-induced necrosis. Necrostatin-1 inhibits RIP1 and blocks TNFα-induced necrosis of FADD-deficient Jurkat cells with an EC50 value of 490 nM.
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