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UbpbioSupplier Diversity Partner NECROSTATIN-1, 5MG DFS Item

Manufacturer:  UbpbioSupplier Diversity Partner F7100

Inhibitors – Necrostatin-1 (UBPBio catalog# F7100, F7101) – Necrostatin-1 is a potent inhibitor of necroptosis, a programmed and caspase-independent cell death mechanism. The death domain receptor-associated serine/threonine kinase RIP1 is essential for TNFα-induced necrosis. Necrostatin-1 inhibits RIP1 and blocks TNFα-induced necrosis of FADD-deficient Jurkat cells with an EC50 value of 490 nM.

Catalog No. 50-112-6905


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