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Cayman Chemical Necrostatin-1 Inactive Contro
Supplier: Cayman Chemical 211921 MG
A demethylated variant of necrostatin-1 that inhibits IDO; ~ 100-fold less effective than Nec-1 in inhibiting RIP1 kinase in vitro and 10-fold less potent than Nec-1 in a mouse necroptosis assay; inhibits TNF-induced systemic inflammatory response syndrome in vivo
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