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Enzo Life Sciences Necrox-5. hydrochloride (1mg)
SDP

Supplier:  Enzo Life Sciences ALX430247M001

Encompass_Preferred

Cell permeable necrosis inhibitor with antioxidant activity. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1μM NecroX™-5 prevented ~50% cell death in H9C2 cells exposed to 400μM t-BuOOH for 2 hours LDH assay used). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro, as well as CCl4 -induced acute liver injury and chronic liver fibrosis in rodent models. Alternative name: [5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(tetrahydro-pyran-4-ylmethyl)-amine. Purity: ≥96% (HPLC, TLC). Appearance: Yellow solid. Solubility: Soluble in DMSO (>10mg/ml). Long Term Storage: -20°C.

Catalog No. 50-200-9262


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