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Medchemexpress LLC Nelfinavir mesylate | 159989-65-8 | C33H49N3O7S2 | 25 MG
Supplier: Medchemexpress LLC 25MGHY15287A
Nelfinavir Mesylate, also known as AG 1343 Mesylate, is a potent and orally bioavailable HIV-1 protease inhibitor. It is also described as a broad-spectrum anticancer agent and an inhibitor of SARS-CoV 3CLpro.
- Potent HIV-1 protease inhibitor (Ki=2 nM)
- Inhibits proliferation of multiple myeloma cells (IC50 of 1-5 μM)
- Triggers apoptosis of myeloma cell lines
- Decreases phosphorylation of AKT, STAT-3, ERK1/2
- Activates the pro-apoptotic pathway of the unfolded protein response system
- Inhibits SARS-CoV 3CLpro (IC50 of 35.93 μM)
- Decreases multiple myeloma cell growth in animal models
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