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Medchemexpress LLC Nelociguat (BAY60-4552) | 625115-52-8 | 99.7% | C19H17FN8O2 | 50 MG
SDP

Catalog No. 5000433041
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Nelociguat (BAY60-4552) is a light yellow to yellow solid compound with a molecular weight of 408.39. Intended for research use only, it acts as a stimulator of nitric oxide sensitive soluble guanylate cyclase.

  • Metabolite of riociguat, formed via cytochrome P450 isoenzymes.
  • Decreases urine output and improves survival in spontaneously hypertensive stroke-prone rats.
  • Reduces microalbuminuria and attenuates the rise in mean arterial pressure at higher doses.
  • Dose-dependently decreased urine output during a 7-week treatment.
  • Combination therapy with vardenafil showed synergistic beneficial effects.

Catalog No. 50-004-33041 Supplier Medchemexpress LLC Supplier No. HY7823750MG
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Nelociguat (BAY60-4552) is a light yellow to yellow solid compound with a molecular weight of 408.39. Intended for research use only, it acts as a stimulator of nitric oxide sensitive soluble guanylate cyclase.

  • Metabolite of riociguat, formed via cytochrome P450 isoenzymes.
  • Decreases urine output and improves survival in spontaneously hypertensive stroke-prone rats.
  • Reduces microalbuminuria and attenuates the rise in mean arterial pressure at higher doses.
  • Dose-dependently decreased urine output during a 7-week treatment.
  • Combination therapy with vardenafil showed synergistic beneficial effects.

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