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Medchemexpress LLC Neomangiferin | 64809-67-2 | 584.48 | 20 MG
Supplier: Medchemexpress LLC HYN072320MG
Neomangiferin is an orally active natural flavonoid known for its multifaceted biological activities, including amelioration of non-alcoholic fatty liver disease (NAFLD), anti-colitis effects, and anti-aging properties. It also shows promise in preventing aseptic loosening of prostheses.
- Partially ameliorates non-alcoholic fatty liver disease (NAFLD) by regulating gene expression related to free fatty acid uptake and lipid oxidation.
- Exhibits anti-colitis effects by inhibiting Th17/Treg cell differentiation.
- Exerts anti-aging and lifespan-extending effects by upregulating bas-1, which activates autophagy, IIS, and MAPK pathways.
- May prevent aseptic loosening of prostheses after total joint arthroplasty due to anti-inflammatory and osteoclastogenesis-inhibiting properties.
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