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Medchemexpress LLC Neomycin (sulfate) (Standard) | 1405-10-3 | 99.9% | 1 G
Supplier: Medchemexpress LLC HYB04701G
Neomycin sulfate is an aminoglycoside antibiotic that functions by irreversibly binding to the nuclear 30S ribosomal subunit, which blocks bacterial protein synthesis. It is utilized in cancer research and has various biochemical inhibitory actions.
- Acts as a phospholipase C (PLC) inhibitor.
- Inhibits the nuclear translocation of angiogenin and its associated cell proliferation and angiogenesis.
- Can inhibit IP3-mediated Ca2+ release.
- Can inhibit MgATP-dependent Ca2+ uptake.
- Can inhibit electrical excitation-evoked skeletal muscle Ca2+ transients.
- Prolonged exposure can deplete gut microbiota in specific mouse models.
- May cause hearing impairment and kidney damage with prolonged exposure.
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