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Cayman Chemical Nepodn 10mg
SDP

Supplier:  Cayman Chemical 27611 10MG

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ABlactamase inhibitor (Kis 29-110 nM for class A and class C enzymes) selective for bacterialBlactamases over a panel of mammalian serine proteases (IC50s 1000 M) potentiates the activity of biapenem against K pneumonia expressing KPC-2 at 0 02 g/ml potentiates the activity of carbapenem antibiotics against clinical isolates of various bacteria (MICs 0 06-4 and 4-64 g/ml in the presence and absence of compound respectively) reduces the number of CFUs in the lung in a neutropenic mouse lung infection model when used in combination with biapenem or meropenem at 50 mg/kg

Catalog No. 50-293-9809


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