Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000401585

Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 50 MG
SDP

Catalog No. 5000401585
Encompass_Preferred

Neratinib maleate (HKI-272 maleate) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor. It is intended for research use only.

  • Inhibits HER2 and EGFR with IC50s of 59 nM and 92 nM, respectively.
  • Demonstrates antiproliferative effects in cell lines with high HER-2 levels.
  • Arrests cell cycle at G1-S phase in BT474 cells.
  • Inhibits MAPK and Akt phosphorylation, and induces p27.
  • Exhibits anticancer activities against HER-2 or EGFR expressing cancer cells in vivo.
  • Reduces tumor growth in xenograft models.

Catalog No. 50-004-01585 Supplier Medchemexpress LLC Supplier No. HY32721B50MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Neratinib maleate (HKI-272 maleate) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor. It is intended for research use only.

  • Inhibits HER2 and EGFR with IC50s of 59 nM and 92 nM, respectively.
  • Demonstrates antiproliferative effects in cell lines with high HER-2 levels.
  • Arrests cell cycle at G1-S phase in BT474 cells.
  • Inhibits MAPK and Akt phosphorylation, and induces p27.
  • Exhibits anticancer activities against HER-2 or EGFR expressing cancer cells in vivo.
  • Reduces tumor growth in xenograft models.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.