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Cayman Chemical Nethyl PRfluoroctnsulfon 100mg

Supplier: Cayman Chemical 37263100 MG

A dopamine D3 receptor agonist selective for dopamine D3 over dopamine D2 receptors (EC50s 38 and 10000 nM respectively inBarrestin recruitment assays using CHO-K1 cells expressing the human receptors) dopamine D1 D4 and D5 receptors and a panel of 45 GPCRs transporters and ion channels at 10 UM inhibits forskolin-induced cAMP accumulation in HEK293 cells expressing the human dopamine D3 receptor (IC50 86 nM) induces phosphorylation of ERK in CHO-K1 cells expressing the human dopamine D3 receptor (EC50 21 nM) protects against 6-OHDA-induced cell death in human iPSC-derived cells differentiated into dopaminergic neurons at 50 nM
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