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Medchemexpress LLC Neticonazole hydrochloride | 130773-02-3 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HY12836510MM/1ML
Neticonazole hydrochloride is an imidazole derivative that acts as a potent and long-acting antifungal agent, also exhibiting anti-infection and anti-cancer effects. In vitro, it decreases Alix, Rab27a, and nSMase2 levels, and inhibits p-ERK. It demonstrates potent, dose-dependent inhibition of exosome release from C4-2B cells, functioning as an orally active exosome biogenesis and secretion inhibitor. In vivo, it improved survival in intestinal dysbacteriosis mice with colorectal cancer xenograft tumors by increasing apoptosis.
- Potent and long-acting antifungal agent
- Exhibits anti-infection and anti-cancer effects
- Decreases Alix, Rab27a, and nSMase2 levels
- Inhibits p-ERK levels
- Potent exosome release inhibitor
- Orally active exosome biogenesis and secretion inhibitor
- Improves survival in colorectal cancer xenograft models
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