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Medchemexpress LLC Neuromedin N (swine spinal cord), 2-L-lysine-, triacetate (salt) | 141863-45-8 | 99.69% | 807.03 | 5 MG
Supplier: Medchemexpress LLC HYP1256C5MG
JMV 449 acetate is a potent neurotensin receptor agonist. It has an IC50 of 0.15 nM for inhibiting 125I-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. This compound also exhibits highly potent and long-lasting hypothermic and analgesic effects in mice.
- Potent neurotensin receptor agonist
- IC50 of 0.15 nM for inhibiting 125I-neurotensin binding to neonatal mouse brain
- EC50 of 1.9 nM in contracting the guinea-pig ileum
- Highly potent and long-lasting hypothermic effects
- Highly potent and long-lasting analgesic effects
- Shows analgesic effect in male Swiss albino mice
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