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Medchemexpress LLC NF-56-EJ40 | 2380230-73-7 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HY13024610MM/1ML
NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist. It exhibits an IC50 of 25 nM and a Ki of 33 nM for human SUCNR1, and high affinity for humanized rat SUCNR1 (Ki 17.4 nM). The compound shows minimal activity towards rat SUCNR1, but increases the thermal stability of both humanized rat and human SUCNR1. It has a molecular weight of 443.54, formula C27H29N3O3, and appears as an off-white to gray solid.
- Potent and highly selective SUCNR1 (GPR91) antagonist
- Targets human and humanized rat SUCNR1
- Increases thermal stability of SUCNR1
- Off-white to gray solid
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