Enzo Life Sciences NF-kappaB SN50 cell permeable inhibitory peptide (0.5mg). CAS: 213546-53-3

Supplier:  Enzo Life Sciences BMLP6000005

Sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to a peptide cell-permeablization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). Peptide inhibits translocation of the NF-κB active complex into the nucleus. In mouse endothelial LE-II cells induced with LPS, inhibition of NF-κB nuclear translocation was 88% at 50µg/ml (18 µM). In human monocytic THP-1 cells induced by LPS or TNFα there was 85% inhibition at 100µg/ml. Sold under license from Vanderbilt University. Purity: ≥97% (HPLC). Solubility: Soluble in water, 100% ethanol or 50% ethanol. Long Term Storage: -20°C.

Catalog No. 50-201-1361