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ABclonal Technology NFYA Rabbit mAb

Supplier: ABclonal Technology A25583100UL
The protein encoded by this gene is one subunit of a trimeric complex forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes Subunit A associates with a tight dimer composed of the B and C subunits resulting in a trimer that binds to DNA with high specificity and affinity The sequence specific interactions of the complex are made by the A subunit suggesting a role as the regulatory subunit In addition there is evidence of post-transcriptional regulation in this gene product either by protein degradation or control of translation Further regulation is represented by alternative splicing in the glutamine-rich activation domain with clear tissue-specific preferences for the two isoforms
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