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Cayman Chemical nglca ctodoa nc Mamsn 50mg

Supplier: Cayman Chemical 2504950 MG

A FAK inhibitor selective for FAK over 261 kinases inhibits FAK autophosphorylation at Y397 in OVCAR8 ovarian U87MG glioblastoma and A549 lung cancer cell lines (IC50s 15 8.5 and 12 nM respectively) induces apoptosis decreases viability (IC50 25 UM) and inhibits colony formation in L3.6P1 cells leads to lower tumor weight and fewer metastases in an orthotopic mouse model of uterine cancer at 75 mg/kg per day
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