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Cayman Chemical nglca pubscns Subrosn 100mg

Supplier: Cayman Chemical 35035100 MG

A derivative of maytansine cytotoxic to SK-BR-3 cells (IC50 3 3 nM) selectivity cytotoxic to a variety of CD205-expressing human cancer cells (EC50s 0 1-1 32 nM) over non-CD205-expressing cells (EC50s 14 2-22 66 nM) and reduces tumor growth in various mouse xenograft and PDX cancer models when conjugated to a humanized CD205-targeting monoclonal antibody
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