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Medchemexpress LLC NH-bis(C1-PEG1-Boc) | 2171072-53-8 | 99.7% | C17H33NO6 | 100 MG
Supplier: Medchemexpress LLC HY140252100MG
NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker, instrumental in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These innovative molecules are designed with two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism allows PROTACs to effectively harness the intracellular ubiquitin-proteasome system for the selective degradation of target proteins, offering a novel approach in drug discovery and therapeutic development.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects E3 ubiquitin ligase and target protein ligands
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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