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Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 50 MG
Supplier: Medchemexpress LLC HY14055150MG
NH-bis(PEG3-azide) is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups or strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Contains an azide group, facilitating click chemistry reactions.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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