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Medchemexpress LLC Ni-57 | 1883548-89-7 | 99.4% | 383.42 | 100 MG
SDP

Catalog No. 5000400792
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NI-57 is a chemical probe and an inhibitor of bromodomain and plant homeodomain finger-containing (BRPF) family of proteins. It has IC50s of 3.1, 46, and 140 nM for BRPF1, BRPF2 (BRD1), and BRPF3, respectively.

  • Inhibits BRPF1, BRPF2 (BRD1), and BRPF3 with varying IC50 values.
  • Binds to the BRD of BRPF1, BRD1, and BRPF3.
  • Shows less active effect on BRD9 and BRD4 (BD1), and TRIM24.
  • Inhibits BRPF BRDs in the nucleus.
  • Has favorable oral bioavailability in mice.

Catalog No. 50-004-00792 Supplier Medchemexpress LLC Supplier No. HY19537100MG
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NI-57 is a chemical probe and an inhibitor of bromodomain and plant homeodomain finger-containing (BRPF) family of proteins. It has IC50s of 3.1, 46, and 140 nM for BRPF1, BRPF2 (BRD1), and BRPF3, respectively.

  • Inhibits BRPF1, BRPF2 (BRD1), and BRPF3 with varying IC50 values.
  • Binds to the BRD of BRPF1, BRD1, and BRPF3.
  • Shows less active effect on BRD9 and BRD4 (BD1), and TRIM24.
  • Inhibits BRPF BRDs in the nucleus.
  • Has favorable oral bioavailability in mice.

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